US Patent Issued to Precision Biosciences on Oct. 21 for "Genetically-modified T cells comprising a modified intron in the T cell receptor alpha gene" (North Carolina Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,613, issued on Oct. 21, was assigned to Precision Biosciences Inc. (Durham, N.C.).

"Genetically-modified T cells comprising a modified intron in the T cell receptor alpha gene" was invented by Derek Jantz (Durham, N.C.), James Jefferson Smith (Morrisville, N.C.) and Clayton Beard (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a genetically-modified T cell comprising in its genome a modified human T cell receptor alpha gene. The modified T cell receptor alpha gene comprises an exogenous sequence of interest inserted into an intron within the T cell receptor alpha gene that is positioned 5' upstream of TRAC...