US Patent Issued to Praxis Precision Medicines on March 25 for "Dynamic clamps and methods of use thereof" (Australian Inventor)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,259,378, issued on March 25, was assigned to Praxis Precision Medicines Inc. (Boston).

"Dynamic clamps and methods of use thereof" was invented by Steven Petrou (Eltham, Australia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods for determining the phenotype (e.g., gain-of-function or loss-of-function) of a mutation in an ion channel or receptor by using a dynamic voltage clamp. The invention also features methods of determining whether a mutation is a gain-of-function or loss-of-function mutation and treating a disease or disorder associated with the particular gain-of-function or loss-of-function mutation."

The p...