ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,466, issued on March 18, was assigned to Pramand LLC (Bedford, Mass.).
"Single solution hydrogels with covalent bonding formed in situ, composition design and medical procedures using the hydrogels" was invented by Michael Bassett (Hampton, N.H.) and Pria Sawhney (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions, methods, and applications for single component systems for the formation of in situ hydrogels are described. The single component systems are effective for forming stable, single solutions containing precursors providing both electrophilic and nucleophilic groups that chemically crosslink on contact with physiol...