ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,481, issued on Sept. 30, was assigned to Portsmouth Merger Sub II LLC (Boston).

"Anti-TREM2 antibodies and related methods" was invented by Michel Streuli (Atherton, Calif.), Venkataraman Sriram (Berkeley, Calif.), Aritra Pal (San Carlos, Calif.) and Leonard G. Presta (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are anti-TREM2 antibodies and related methods of making and using anti-TREM2 antibodies. Also provided are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e.g., cancer, comprising killing, disabling, or depleting non-stimulat...