US Patent Issued to Portland State University on July 15 for "Seminaphthofluorophore-selenium probes for thioredoxin reductase" (Oregon Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,923, issued on July 15, was assigned to Portland State University (Portland, Ore.).

"Seminaphthofluorophore-selenium probes for thioredoxin reductase" was invented by Robert M. Strongin (Portland, Ore.), Jorge O. Escobedo Cordova (Portland, Ore.) and Tendai Mafireyi (Portland, Ore.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Seminaphthofluorophore-selenium probes are disclosed. The probes include a seminaphthofluorophore scaffold substituted with at least one diselenide moiety having a formula -Y-C(Q)O-(CH2)m-Se-Se-(CH2)n-ORf, where Rf is hydrogen or C1-C3 alkyl, Q is O or S, Y is O or N(Rg) where Rg is H or alkyl, andn independently are integers...