ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,571, issued on Nov. 25, was assigned to PONTIS BIOLOGICS INC. (Huntington, N.Y.).

"Enzyme based compositions and methods for removing dental calculi" was invented by Dennis C. Mynarcik (Huntington, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compositions and formulations comprising enzymes or other biocatalyst that cleave surface-accessible DNA polymers and/or glycoprotein carbohydrate chains at galactose residues in dental calculus, and optionally further include one or more proteolytic enzymes, thereby destroying the structural integrity of the calculus, and allowing it to be readily removed without requiring special treatmen...