US Patent Issued to POLITECNICO DI MILANO on July 15 for "Device, method and composition for transfection of cells with nucleic acids" (Italian Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,157, issued on July 15, was assigned to POLITECNICO DI MILANO (Milan).

"Device, method and composition for transfection of cells with nucleic acids" was invented by Gabriele Candiani (Milan), Nina Bono (Sciacca, Italy) and Federica Ponti (Induno Olona, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a method, a composition and a device for the introduction of exogenous nucleic acids into eukaryotic cells by non-viral vectors (non-viral transfection). The method according to the invention is based on application of a high-frequency oscillatory motion to a solution containing nucleic acids and cationic polymers or lipids to obtain p...