US Patent Issued to PMV PHARMACEUTICALS on Sept. 30 for "Methods and compounds for restoring mutant p53 function" (New Jersey, Connecticut Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,406, issued on Sept. 30, was assigned to PMV PHARMACEUTICALS INC. (Princeton, N.J.).

"Methods and compounds for restoring mutant p53 function" was invented by Binh Vu (North Caldwell, N.J.), Romyr Dominique (East Brunswick, N.J.), Hongju Li (Edison, N.J.), Bruce Fahr (East Windsor, N.J.) and Andrew Good (Wallingford, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer. The present disclosure describes compounds and methods to recover wild-type function to p53 mutants. The compounds of the present invention can bind to mutant p53 and restore the abi...