ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,444, issued on Dec. 30, was assigned to Plexxikon Inc. (South San Francisco, Calif.).

"Compounds and methods for CD73 modulation and indications therefor" was invented by Mark Vander Wal (Berkeley, Calif.), John Buell (San Francisco), Xinping Han (Berkeley, Calif.), Yongil Jin (New York), Guoxian Wu (Foster City, Calif.), Songyuan Shi (Fremont, Calif.), Wayne Spevak (Berkeley, Calif.), Jack Walleshauser (Berkeley, Calif.), Jiazhong Zhang (Foster City, Calif.), Ying Zhang (Fremont, Calif.) and Zuojun Guo (Pasadena, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compounds capable of modulating CD73, of Formula I:or a pharmaceutica...