ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,888, issued on July 22, was assigned to Pioneer Hi-Bred International Inc. (Johnston, Iowa).
"CRISPR-Cas systems for genome editing" was invented by Zhenglin Hou (Ankeny, Iowa), Tautvydas Karvelis (Paberze, Lithuania), Virginijus Siksnys (Vilnius, Lithuania) and Joshua K Young (Johnston, Iowa).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided for genome modification of a target sequence in the genome of a cell, using a novel Cas endonuclease. The methods and compositions employ a guide polynucleotide/endonuclease system to provide an effective system for modifying or altering target sequences within the genome of a ...