ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,067, issued on April 22, was assigned to Phenolics LLC (Omaha, Neb.).

"Formulations of creatine and cyclodextrin exhibiting improved bioavailability" was invented by Michael S Tempesta (El Granada, Calif.) and F. Joseph Daugherty (Omaha, Neb.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Formulations of creatine, preferably phosphocreatine and most preferably disodium phosphocreatine, combined with cyclodextrin exhibit improved uptake across digestive mucosa, including intestinal, esophageal, and stomach mucosa. In particular, the formulations of the present invention are designed for protection of the cyclodextrin as it comes in contact with gastri...