US Patent Issued to Pharmacosmos Holding on Nov. 25 for "Morphic forms of trilaciclib and methods of manufacture thereof" (Dutch, American Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,855, issued on Nov. 25, was assigned to Pharmacosmos Holding A/S (Holbaek, Denmark).

"Morphic forms of trilaciclib and methods of manufacture thereof" was invented by Stephen Schneider (Raleigh, N.C.), Alexander Smith (Apex, N.C.), Hannah S. White (Chapel Hill, N.C.), Jay Copeland Strum (Hillsborough, N.C.) and Jaroslaw Mazurek (Amsterdam).

According to the abstract* released by the U.S. Patent & Trademark Office: "An advantageous isolated morphic form of trilaciclib which is 2'-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one, for example in the form of a dihydrochloride salt or a dihydroc...