ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,527,798, issued on Jan. 20, was assigned to Pharmacosmos Holding A/S (Holbaek, Denmark).

"Preservation of immune response during chemotherapy regimens" was invented by Jessica A. Sorrentino (Durham, N.C.), Anne Y. Lai (Cary, N.C.), Jay C. Strum (Hillsborough, N.C.) and Patrick Joseph Roberts (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The addition of a selective, fast-acting, short half-life CDK 4/6 inhibitor in a very specific dosage regimen to the combination of chemotherapy with a checkpoint inhibitor provides superior results in the treatment of a tumor or cancer. The unexpected discovery is that the short pulsatile specifically-tim...