ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,689, issued on Nov. 4, was assigned to Pfizer Inc. (New York).

"Escherichia coli compositions and methods thereof" was invented by Robert G. K. Donald (South Orange, N.J.) and Rosalind Pan (Morris Plains, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention provides a polypeptide derived from E. coli or a fragment thereof, including compositions and methods thereof. In one embodiment, the compositions comprise a polypeptide derived from E. coli or a fragment thereof, and modified O-polysaccharide molecules derived from E. coli lipopolysaccharides or conjugates thereof. In a further aspect, the compositions further comprise modified O-po...