ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,512,183, issued on Dec. 30, was assigned to Personalis Inc. (Fremont, Calif.).
"Estimating tumor purity from single samples" was invented by Nicholas Phillips (Fremont, Calif.) and Jason Harris (Fremont, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides methods for estimating tumor purity from tumor samples without use of matched-normal controls. A set of genomic regions are identified based on a nucleic acid sequence data that is aligned to a reference genome. Each genomic region of the set of genomic regions includes one or more nucleotide-sequence variants relative to a corresponding genomic region of the reference genome....