US Patent Issued to Personal Genome Diagnostics on June 17 for "Methods and systems for identification and prioritization of mutation-derived neoantigens" (Maryland Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,361, issued on June 17, was assigned to Personal Genome Diagnostics Inc. (Baltimore).

"Methods and systems for identification and prioritization of mutation-derived neoantigens" was invented by Victor Velculescu (Baltimore), Theresa Zhang (Baltimore), James Robert White (Baltimore) and Luis Diaz (Ellicott City, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Cancer immunology provides promising new avenues for cancer treatment but validation of potential neoantigens to target is costly and expensive. Analysis of MHC binding affinity, antigen processing, similarity to known antigens, predicted expression levels (as mRNA or proteins), self-similari...