ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,594, issued on Nov. 18, was assigned to PEKING UNIVERSITY (Beijing).

"Chemical tagging-based method for modified nucleoside sequencing, enrichment, and measurement" was invented by Guifang Jia (Beijing), Ye Wang (Beijing) and Shunqing Dong (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a chemical tagging-based method for modified nucleoside sequencing, enrichment, and measurement, comprising reacting a thiol compound with an N-hydroxymethyl chemically modified nucleoside, then using a chemical tag such as biotin to perform tagging, and then enriching and sequencing or measuring. In the method of the present invention, selective ...