ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,435, issued on Dec. 9, was assigned to Paradigm Diagnostics (Ann Arbor, Mich.).
"Sample DNA preparation using nuclease" was invented by Scott Morris (Phoenix).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosed technology relates to a method of analyzing DNA from a biological sample. In one aspect, the method comprises obtaining a sample a sample from a subject, the sample comprising DNA that comprises double-stranded DNA (dsDNA) suspected of having one or more thymine lesions formed by deamination of 5-methylcytosines, wherein the thymine lesions form base pair mismatches in the dsDNA, contacting the sample with a nuclease that digests dsDNA...