US Patent Issued to Pairwise Plants Services on Sept. 30 for "Methods and compositions for modification of protospacer adjacent motif specificity of CAS12A" (North Carolina Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,636, issued on Sept. 30, was assigned to Pairwise Plants Services Inc. (Durham, N.C.).

"Methods and compositions for modification of protospacer adjacent motif specificity of CAS12A" was invented by David Gerhard Schwark (New Hill, N.C.), Joanne Hunt (Wake Forest, N.C.) and Joseph Matthew Watts (Cary, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to variants of Cas12a nucleases having altered protospacer adjacent motif recognition specificity. The invention further relates to methods of making CRISPR-CAS nuclease variants and methods of modifying nucleic acids using the variants."

The patent was filed on July 8, 2024, ...