US Patent Issued to Pacific Biosciences of California on Aug. 19 for "Protected dye-labeled reagents" (California, Oregon Inventors)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,834, issued on Aug. 19, was assigned to Pacific Biosciences of California Inc. (Menlo Park, Calif.).

"Protected dye-labeled reagents" was invented by Lubomir Sebo (Redwood City, Calif.), Honey Osuna (San Francisco), Stephen Yue (Eugene, Ore.) and Yuri Lapin (Newark, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Labeled nucleotide analogs comprising at least one avidin protein, at least one dye-labeled compound, and at least one nucleotide compound are provided. The analogs are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as sin...