ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,431, issued on Jan. 13, was assigned to OXFORD UNIVERSITY INNOVATION Ltd. (Oxford, Great Britain).
"HBV vaccine" was invented by Eleanor Barnes (Oxford, Great Britain) and Senthil Chinnakannan (Oxford, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a multi-HBV immunogen viral vector vaccine comprising: a viral vector comprising an immunogen expression cassette, wherein the expression of a protein encoded by the expression cassette is arranged to be driven by a promoter, wherein the immunogen expression cassette encodes: a) HBV Core; b) a modified HBV polymerase (Pmut), wherein the modification is a mutation to ...