ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,646, issued on Oct. 21, was assigned to Oxford Nanopore Technologies PLC (Oxford, Great Britain).
"SSB method" was invented by James White (Oxford, Great Britain), Ruth Moysey (Oxford, Great Britain) and Mihaela Misca (Oxford, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method of characterising a target polynucleotide using a single-stranded binding protein (SSB). The SSB is either an SSB comprising a carboxy-terminal (C-terminal) region which does not have a net negative charge or a modified SSB comprising one or more modifications in its C-terminal region which decreases the net negative charge of the C-...