US Patent Issued to OTSUKA PHARMACEUTICAL, TAIHO PHARMACEUTICAL on Nov. 4 for "Pyrazolo[3,4-bpyrazine SHP2 phosphatase inhibitors" (British, Japanese Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,640, issued on Nov. 4, was assigned to OTSUKA PHARMACEUTICAL Co. LTD. (Tokyo) and TAIHO PHARMACEUTICAL Co. LTD. (Tokyo).

"Pyrazolo[3,4-bpyrazine SHP2 phosphatase inhibitors" was invented by Steven Howard (Cambridge, Great Britain), John Walter Liebeschuetz (Cambridge, Great Britain) and Tadashi Shimamura (Tsukuba, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides new pyrazine derivatives of formula (I):or a tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein. The invention also provides pharmaceutical compositions comprising said compounds and to the use of said...