US Patent Issued to Oslo Universitetssykehus HF on April 29 for "Chimeric antigen receptors (CARS) that bind osteosarcoma and their use in medicine" (Norwegian Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,642, issued on April 29, was assigned to Oslo Universitetssykehus HF (Oslo, Norway).

"Chimeric antigen receptors (CARS) that bind osteosarcoma and their use in medicine" was invented by Else Marit Inderberg (Oslo, Norway), Sebastian Walchli (Oslo, Norway) and Oyvind S. Bruland (Oslo, Norway).

According to the abstract* released by the U.S. Patent & Trademark Office: "Chimeric antigen receptors (CARs) are provided. When the CARs herein are expressed on the surface of immune cells, such immune cells may be directed to osteosarcoma cells. In a murine intraperitoneal model, the tumor growth was significantly delayed for T cells expressing a CAR comprising a scFv from TP1 or TP3 antibo...