ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,447,165, issued on Oct. 21, was assigned to OSAKA UNIVERSITY (Osaka, Japan).
"Intratumoral vein-formation promoting agent" was invented by Nobuyuki Takakura (Osaka, Japan) and Daisuke Eino (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are agents comprising a phosphatidylcholine as an active ingredient to serve as a vein-formation promoting agent capable of promoting vein-like morphological change of tumor vessels, a vessel-diameter enlarging agent capable of enlarging the diameter of tumor vessels, a blood vessel-connection promoting agent capable of promoting connection of tumor vessels to each other without mediation of a lysop...