US Patent Issued to Orna Therapeutics on May 13 for "Circular RNA encoding chimeric antigen receptors targeting BCMA" (Massachusetts Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,285, issued on May 13, was assigned to Orna Therapeutics Inc. (Watertown, Mass.).

"Circular RNA encoding chimeric antigen receptors targeting BCMA" was invented by Thomas Barnes (Watertown, Mass.), Amy M. Becker (Watertown, Mass.), Brian Goodman (Watertown, Mass.) and Jui Dutta-Simmons (Watertown, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Circular RNA, along with related compositions and methods are described herein. In some embodiments, the inventive circular RNA comprises group I intron fragments, spacers, an IRES, duplex forming regions, and an expression sequence. In some embodiments, the expression sequence encodes an antigen. In som...