US Patent Issued to Orionis Biosciences, VIB VZW, Universiteit Gent on Jan. 13 for "Targeted mutant interferon-gamma and uses thereof" (Belgian, American Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,641, issued on Jan. 13, was assigned to Orionis Biosciences BV (Ghent, Belgium), VIB VZW (Ghent, Belgium) and Universiteit Gent (Ghent, Belgium).

"Targeted mutant interferon-gamma and uses thereof" was invented by Nikolai Kley (Newton, Mass.), Jan Tavernier (Balegem, Belgium), Frank Peelman (Gentbrugge, Belgium) and Lennart Zabeau (Zwijnaarde, Belgium).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates, in part, to chimeric proteins comprising a modified human IFN-Gamma having one or more mutations that confer reduced affinity and/or biological activity that is restorable by attachment to one or more targeting moieties. The ...