ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,225, issued on Sept. 9, was assigned to Orionis Biosciences Inc (Waltham, Mass.), Orionis Biosciences BV (Ghent, Belgium), VIB VZW (Ghent, Belgium) and Universiteit Gent (Ghent, Belgium).

"Modulation of dendritic cell lineages" was invented by Nikolai Kley (Waltham, Mass.), Jan Tavernier (Balegem, Belgium), Anje Cauwels (Merelbeke, Belgium), Lennart Zabeau (Zwijnaarde, Belgium) and Erik Depla (Zwijnaarde, Belgium).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates, in part, to agents, chimeric proteins and chimeric protein complexes that bind a plasmacytoid dendritic cell (pDC), e.g. Clec4C and their use as diagnostic and t...