ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,308, issued on March 25, was assigned to Ono Pharmaceutical Co. Ltd. (Osaka, Japan).

"Benzene derivative" was invented by Shoji Nojima (Osaka, Japan), Kenji Sasaki (Osaka, Japan), Tohru Kambe (Osaka, Japan), Takashi Konemura (Osaka, Japan) and Yoshikazu Goto (Osaka, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A compound represented by general formula (I) (in the formula, all symbols are as described in the description) or a salt thereof has a potent nerve-protecting and/or -repairing activity, and therefore can be used as a therapeutic agent for neuropathy (e.g., chronic inflammatory demyelinating polyneuropathy, Guillain-Barre syndrome, p...