US Patent Issued to Omniox on April 29 for "Modulation of tumor immunity by protein-mediated O 2 delivery" (California Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,285,463, issued on April 29, was assigned to Omniox Inc. (San Francisco).

"Modulation of tumor immunity by protein-mediated O 2 delivery" was invented by Stephen P. L. Cary (San Mateo, Calif.), Ana Krtolica (San Francisco), Natacha Le Moan (San Francisco), Jonathan A Winger (Oakland, Calif.) and Kevin G. Leong (Millbrae, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides methods to modulate hypoxia-mediated tumor immunity by administration of an O2 carrier polypeptide (e.g., an H-NOX protein). The methods of the invention target both hypoxia inducible factor 1 alpha (HIF-1Alpha) pathways and non-HIF-1Alpha pathways of tumor immu...