US Patent Issued to Ohio State Innovation Foundation on June 24 for "Modified nucleic acids, hybrid guide RNAS, and uses thereof" (Ohio Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,433, issued on June 24, was assigned to Ohio State Innovation Foundation (Columbus, Ohio).

"Modified nucleic acids, hybrid guide RNAS, and uses thereof" was invented by Yizhou Dong (Dublin, Ohio) and Bin Li (Columbus, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure generally relates to genome editing systems and methods and compounds and compositions for use in Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) genome editing systems. Disclosed herein are modified nucleic acids that modulate the activity of genome editing."

The patent was filed on Dec. 18, 2023, under Application No. 18/543,827.

*For furt...