US Patent Issued to Ohio State Innovation Foundation on Feb. 18 for "Modulators of notch signaling and methods of use thereof" (Ohio Inventors)

ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,558, issued on Feb. 18, was assigned to Ohio State Innovation Foundation (Columbus, Ohio).

"Modulators of notch signaling and methods of use thereof" was invented by Thomas J. Magliery (Columbus, Ohio), Mikhail M. Dikov (Dublin, Ohio), David Carbone (Hilliard, Ohio), Nicholas Long (Columbus, Ohio), Brandon Sullivan (Gahanna, Ohio) and Elena Tchekneva (Dublin, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are Notch-modulating peptides (including monomers and multimers) capable of increasing or decreasing an immune response in a subject, compositions comprising the peptides, and methods of use thereof."

The patent was filed on ...