ALEXANDRIA, Va., Feb. 12 -- United States Patent no. 12,221,471, issued on Feb. 11, was assigned to Ohio State Innovation Foundation (Columbus, Ohio).
"Nanocarriers for lung inflammation therapy" was invented by Natalia Higuita-Castro (Columbus, Ohio), Daniel Gallego-Perez (Columbus, Ohio), Samir Ghadiali (Upper Arlington, Ohio), Joshua Englert (Powell, Ohio) and Chandan Sen (Columbus, Ohio).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are lung-targeted extracellular vesicles (EVs) loaded with an anti-inflammatory cargo, as well as compositions, systems, and methods for making same. The disclosed EVs can contain a lung targeted ligand, such as a fusion protein containing a lung targeting moiety. A...