ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,448, issued on Jan. 13, was assigned to Oculis Operations Sarl (Lausanne, Switzerland).
"Preparation of solid cyclodextrin complexes for ophthalmic active pharmaceutical ingredient delivery" was invented by Thorsteinn Loftsson (Reykjavik, Iceland) and Zoltan Fulop (Budapest, Hungary).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmi...