US Patent Issued to OCEAN UNIVERSITY OF CHINA on Jan. 13 for "Brefeldin a derivatives, preparation method and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,590, issued on Jan. 13, was assigned to OCEAN UNIVERSITY OF CHINA (Shandong, China).

"Brefeldin a derivatives, preparation method and use thereof" was invented by Changlun Shao (Shandong, China), Changyun Wang (Shandong, China) and Yaoyao Jiang (Shandong, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to the field of medicinal chemistry, and specifically to brefeldin A derivatives represent by Formula (I) and its use in the inhibition of tumor proliferation activity. The new compounds provided herein are prominent in the prevention or treatment of hyperproliferative diseases, including liver cancer, leukemia, bre...