ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,795, issued on Sept. 16, was assigned to Nxera Pharma UK Ltd. (Cambridge, Great Britain).
"4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators" was invented by John Andrew Christopher (Cambridge, Great Britain), Miles Stuart Congreve (Melbourn Royston, Great Britain), Sarah Joanne Aves (Cambridge, Great Britain) and Benjamin Gerald Tehan (Cambridge, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosures herein relate to novel compounds of formulawherein R1, R2, R3 and R4 and n are defined herein, and their use in treating, preventing, ameliorating, controlling or reducing the risk of inflammation, neurological or psychiat...