ALEXANDRIA, Va., Feb. 5 -- United States Patent no. 12,216,123, issued on Feb. 4, was assigned to Nuvance Health (Danbury, Conn.).

"Extracellular vesicle derived MASP-2 directed cancer treatment methods" was invented by Richard C. Frank (Fairfield, Conn.), Shatovisha Dey (Danbury, Conn.) and Deep Siddhartha Pandya (Stamford, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides for cancer treatment methods related to the unexpected discovery of the role of mannan-binding protein-associated serine protease-2 (MASP-2) in cancer. Improved cancer treatment methods are disclosed that are determined by measuring changes in levels of MASP-2, a previously unknown biomarker for cancer. ...