ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,442,006, issued on Oct. 14, was assigned to Novel Biotechnology USA Inc. (Vancouver, Wash.).

"Expression system for product manufacturing" was invented by Santhosh Thomas Kallivalappil (Winnipeg, Canada) and Matthew Weinstock (Camas, Wash.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides engineered bacterial cells having one or more genetic modifications that result in increased production of expression products, such as increased production of plasmids with reduced occurrence of plasmid concatemers or multimers. Also disclosed herein are expression systems for product manufacturing in media having reduced antibiotic concen...