US Patent Issued to Novartis on March 25 for "5-hydroxy-7-oxabicyclo[2.2.1heptane-2-carboxamide derivatives for inducing chondrogenesis for treating joint damage" (California Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,243, issued on March 25, was assigned to Novartis AG (Basel, Switzerland).

"5-hydroxy-7-oxabicyclo[2.2.1heptane-2-carboxamide derivatives for inducing chondrogenesis for treating joint damage" was invented by James Paul Lajiness (San Diego) and Andrew Valiere (Descanso, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides 5-hydroxy-7-oxabicyclo[2.2.1]heptane-2-carboxamide derivatives of Formula (1) wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds. The compounds are used for inducing chondrogenesis, in methods of treating or preve...