US Patent Issued to Northwestern University on Nov. 11 for "Methods for mapping personalized translatome" (Illinois Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,467,048, issued on Nov. 11, was assigned to Northwestern University (Evanston, Ill.).

"Methods for mapping personalized translatome" was invented by Qianru Li (Evanston, Ill.), Haiwang Yang (Evanston, Ill.) and Zhe Ji (Evanston, Ill.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A low-input RNase footprinting approach is described for the rapid quantification of ribosome-protected fragments with 1,000-100,000 cells. The assay uses a simplified procedure for capturing ribosome-RNA complexes based on optimized RNase digestion. It simultaneously maps cytosolic and mitochondrial translation with single-nucleotide resolution."

The patent was filed on Dec. ...