US Patent Issued to NORTHWESTERN UNIVERSITY on June 3 for "Spherical nucleic acids with tailored and active protein coronae" (Illinois, Texas Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,711, issued on June 3, was assigned to NORTHWESTERN UNIVERSITY (Evanston, Ill.).

"Spherical nucleic acids with tailored and active protein coronae" was invented by Chad A. Mirkin (Wilmette, Ill.), Wuliang Zhang (Evanston, Ill.) and Brian R. Meckes (Highland Village, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure is generally related to spherical nucleic acids (SNAs) comprising a protein corona, wherein the SNA comprises (i) a nanoparticle core and (ii) one or more oligonucleotides attached to the surface of the nanoparticle core, wherein the protein corona comprises a plurality of proteins. The disclosure also provides methods of...