US Patent Issued to Northwestern University on June 10 for "Riboswitch-based fluoride sensing in cell-free extract" (Illinois Inventors)

ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,884, issued on June 10, was assigned to Northwestern University (Evanston, Ill.).

"Riboswitch-based fluoride sensing in cell-free extract" was invented by Julius B. Lucks (Evanston, Ill.), Walter M. Thavarajah (Chicago), Adam D. Silverman (Chicago) and Michael C. Jewett (Evanston, Ill.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods and systems for detecting fluoride as a target molecule in a test sample which utilize a cell-protein synthesis (CFPS) reaction and an engineered fluoride-sensing riboswitch. The components used in the disclosed methods and systems may be dried or lyophilized and may be present or immobilized on a pa...