US Patent Issued to NORTHWESTERN UNIVERSITY on Aug. 5 for "Deoxynucleic guanidines (DNG)-modified oligonucleotides and methods of synthesizing deoxynucleic guanidine strands" (American, Canadian Inventors)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,280, issued on Aug. 5, was assigned to NORTHWESTERN UNIVERSITY (Evanston, Ill.).

"Deoxynucleic guanidines (DNG)-modified oligonucleotides and methods of synthesizing deoxynucleic guanidine strands" was invented by Chad A. Mirkin (Wilmette, Ill.), Kacper Skakuj (Durham, N.C.) and Katherine E. Bujold (Magog, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are spherical nucleic acids (SNAs) comprising oligonucleotides comprising one or more modified oligonucleotides, and methods of use thereof. Also disclosed are methods of synthesizing modified oligonucleotides for use in therapeutics, including deoxynucleic guanidine (DNG)-modif...