ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,548,733, issued on Feb. 10, was assigned to New York Structural Biology Center (New York).
"Automating cryo-electron microscopy data collection" was invented by Paul T. Kim (San Francisco) and Tristan Bepler (Hillsborough, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of automated control of a microscope in cryogenic electron microscopy (cryo-EM), wherein the microscope is configured to collect high-magnification micrographs of particles suspended in vitreous ice. Such particles are found in grid squares, and a square contains holes from which high-magnification micrographs are imaged. The method is carried out during an active data colle...