US Patent Issued to New England Biolabs on Oct. 28 for "In vitro cleavage of DNA using argonaute" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,686, issued on Oct. 28, was assigned to New England Biolabs Inc. (Ipswich, Mass.).

"In vitro cleavage of DNA using argonaute" was invented by Nathan Tanner (West Newbury, Mass.) and Eric Hunt (Danvers, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods, kits and compositions, in some embodiments, may include a thermostable DNA guided Argonaute protein for example TtAgo, a thermostable single-stranded DNA binding protein (SSB) for example, extreme thermostable single-stranded DNA binding protein (ET SSB), and, optionally, a strand-displacing polymerase. A SSB may allow (a) Argonaute/guide DNA complexes to substantially enhance cleavage effi...