ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,907, issued on Feb. 10, was assigned to New England Biolabs Inc. (Ipswich, Mass.).

"Compositions and methods relating to synthetic RNA polynucleotides created from synthetic DNA oligonucleotides" was invented by G. B. Robb (Somerville, Mass.), Isaac B. Meek (Hopkinton, Mass.), Dianne S. Schwarz (Watertown, Mass.) and Ezra Schildkraut (Boxford, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided for forming a single RNA polynucleotide from a plurality of DNA oligonucleotides in a single reaction chamber using combined reagents in a single step reaction. DNA polymerase, RNA polymerase and single stranded (ss) DNA...