ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,173, issued on Aug. 26, was assigned to New England Biolabs Inc. (Ipswich, Mass.).
"Enzymatic RNA capping method" was invented by G. Brett Robb (Somerville, Mass.), Siu-Hong Chan (Georgetown, Mass.) and Bijoyita Roy (Medford, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is a method for efficiently capping RNA in vitro. In some embodiments the capping reaction may be done at high temperature using Vaccinia capping enzyme or a variant thereof. In other embodiments, the capping reactions may comprise a capping enzyme from a large virus of amoeba, e.g., Faustovirus, mimivirus or moumouvirus, or a variant thereof. Compositions and...