ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,215, issued on Aug. 5, was assigned to NeuroWave Systems Inc. (Cleveland).

"Intelligent pharmaceutical delivery system with automatic shutoff and method of using" was invented by Stephane Bibian (Cleveland Heights, Ohio) and Tatjana Zikov (Cleveland Heights, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "A system and a method provide closed-loop sedation, anesthesia, or analgesia by monitoring EEG and automatically adjusting delivery of sedative, anesthetic, and/or analgesic drugs to maintain a desired or predetermined level of cortical at all echelons of care. The system and the method further monitor a subject's cortical activity to detect occ...