US Patent Issued to Neptune Biosciences on Nov. 18 for "Orthogonal IL-21 receptor/cytokine systems" (California Inventors)

ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,335, issued on Nov. 18, was assigned to Neptune Biosciences LLC (Newark, Calif.).

"Orthogonal IL-21 receptor/cytokine systems" was invented by Nigel Killeen (Hillsborough, Calif.), Oren Beske (Aromas, Calif.), Benedikt K. Vollrath (San Diego) and Sridhar Govindarajan (Los Altos, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Orthogonal IL-21 receptors and orthogonal IL-21 cytokines are described. The IL-21 receptor-cytokine pairs may include an orthogonal interleukin-21 receptor Alpha chain ("ortho-IL-21RAlpha") that has impaired binding to native interleukin-21 cytokine ("IL-21") and an orthogonal IL-21 cytokine ("ortho-IL-21") that has impa...