ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,671, issued on April 29, was assigned to NCAN Genomics Inc. (Vancouver, Canada).
"Linked target capture" was invented by Joel Pel (Vancouver, Canada) and Andrea Marziali (North Vancouver, Canada).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention generally relates to sequencing library preparation methods. In certain embodiments, two or more template nucleic acids are joined together by a linking molecule, such as a PEG derivative. Identical copies of a nucleic acid fragment or both strands of a duplex fragment may be linked together. The linked nucleic acids are amplified, creating linked amplicons. Emulsion PCR with linked primers creates ...